Fig. 1 · Structure

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Sofosbuvir impurity I

HCV

Sofosbuvir impurity I is a diastereoisomer of Sofosbuvir, an antiviral compound targeting hepatitis C virus (HCV). As a known impurity of Sofosbuvir, this compound is relevant for analytical studies aimed at assessing drug purity and efficacy. It plays a critical role in HCV RNA replication inhibition research and is useful for characterizing the quality of Sofosbuvir formulations in pharmaceutical development.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2164516-85-0
Applications HCV
Formula C21H27FN3O9P
Molecular Weight 515.43
SMILES
O=[P@@](N[C@@H](C)C(OCC)=O)(OC[C@@H]1[C@@H](O)[C@](F)(C)[C@H](N2C=CC(NC2=O)=O)O1)OC3=CC=CC=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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