Fig. 1 · Structure
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Sofpironium bromide
Anticholinergic Agent
Sofpironium bromide is an anticholinergic agent that primarily targets M3 muscarinic receptors in eccrine glands, effectively reducing sweating. This compound is utilized in research focused on primary axillary hyperhidrosis (PAH). Additionally, it demonstrates a high affinity for M1, M2, M4, and M5 muscarinic receptor subtypes, making it a valuable tool for studying various cholinergic pathways and their physiological effects.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1628106-94-4 |
| Applications | Anticholinergic Agent |
| Formula | C22H32BrNO5 |
| Molecular Weight | 470.40 |
| Synonyms | BBI 4000 |
| SMILES | CCOC(C[N+](C)(CC1)C[C@@H]1OC([C@@](C2CCCC2)(C3=CC=CC=C3)O)=O)=O.[Br-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.