Sotalol-d6

Catalog No.: A58553
Stable Isotope
Sotalol-d6 is a deuterium-labeled derivative of Sotalol, a non-selective β-adrenergic receptor antagonist. This compound exhibits potent antiarrhythmic activity, making it valuable for studying pediatric arrhythmias. Additionally, Sotalol-d6 inhibits β-receptors and potassium KCNH2 channels, highlighting its utility in the investigation of cardiac electrophysiology and as a potential antiepileptic agent.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSotalol-d6 is a deuterium-labeled derivative of Sotalol, a non-selective β-adrenergic receptor antagonist. This compound exhibits potent antiarrhythmic activity, making it valuable for studying pediatric arrhythmias. Additionally, Sotalol-d6 inhibits β-receptors and potassium KCNH2 channels, highlighting its utility in the investigation of cardiac electrophysiology and as a potential antiepileptic agent.
Product Information
Catalog NumA58553
FormulaC12H14D6N2O3S
Molecular Weight278.40
CAS Number1246912-17-3
SMILESOC(C1=CC=C(NS(C)(=O)=O)C=C1)CNC(C([2H])([2H])[2H])C([2H])([2H])[2H]
SynonymsMJ 1999-d6
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