SPA4

Name: SPA4
Brand: Adooq Bioscience
SKU: A36131
Rating: 5 (288 reviews)

Catalog No.: A36131

Active peptides

SPA4 is a Toll-like receptor 4 (TLR4)-interacting peptide that specifically inhibits the lipopolysaccharide (LPS)-induced production of the pro-inflammatory cytokine TNF-α. This compound demonstrates its biological activity without adversely affecting cell viability or size. SPA4 is useful in research applications related to inflammation, cytokine signaling, and TLR4-mediated pathways.

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Data Sheet SDS Compound Handling Instructions

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Biological Activity

Description	SPA4 is a Toll-like receptor 4 (TLR4)-interacting peptide that specifically inhibits the lipopolysaccharide (LPS)-induced production of the pro-inflammatory cytokine TNF-α. This compound demonstrates its biological activity without adversely affecting cell viability or size. SPA4 is useful in research applications related to inflammation, cytokine signaling, and TLR4-mediated pathways.

Product Information

Catalog Num	A36131
Formula	C107H145N29O35
Molecular Weight	2397.47
CAS Number	1343908-95-1
Sequence	Gly-Asp-Phe-Arg-Tyr-Ser-Asp-Gly-Thr-Pro-Val-Asn-Tyr-Thr-Asn-Trp-Tyr-Arg-Gly-Glu
Sequence shortening	GDFRYSDGTPVNYTNWYRGE
SMILES	C([C@@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(NCC(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)CCCNC(=N)N)=O)=O)NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC(=O)[C@H]3N(C([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC4=CC=C(O)C=C4)NC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC(CN)=O)CC(O)=O)=O)=O)CCCNC(=N)N)=O)=O)CO)=O)CC(O)=O)=O)=O)[C@@H](C)O)=O)CCC3)[C@@H](C)C)=O)CC(N)=O)=O)=O)[C@@H](C)O)=O)CC(N)=O)=O)C=6C=7C(NC6)=CC=CC7

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