Spautin-1

Catalog No.: A12942

Autophagy Inhibitor

Spautin-1

Spautin-1 Chemical Structure

CAS NO. 1262888-28-7

Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03μM. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 μM.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $70.00

Special Price $63.00

25 mg

Regular Price: $130.00

Special Price $117.00

50 mg

Regular Price: $250.00

Special Price $225.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03μM. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 μM.
Targets
USP10 USP10 USP13
0.6 μM~0.6 μM~0.6 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.87 mL 184.33 mL 368.65 mL
0.5 mM 7.37 mL 36.87 mL 73.73 mL
1 mM 3.69 mL 18.43 mL 36.87 mL
5 mM 0.74 mL 3.69 mL 7.37 mL

*The above data is based on the productmolecular weight 271.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12942
Actions Inhibitor
M. Wt 271.26
Formula C15H11F2N3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1262888-28-7
Synonyms Spautin 1, Spautin1
SMILES FC1=CC(C(NCC2=CC=C(F)C=C2)=NC=N3)=C3C=C1

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