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SPB07935

Antimalarial Agent

SPB07935 is a potent inhibitor of plasmepsin II in Plasmodium falciparum, serving as an effective antimalarial agent. This compound regulates the lifecycle of P. falciparum and demonstrates significant inhibition of Plasmodium strains FcB1 and 3D7, with IC50 values of 8 μM and 4.7 μM, respectively. Its targeted action against key proteolytic pathways makes it a valuable tool for researchers studying malaria and developing new therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	634190-75-3
Applications	Antimalarial Agent
Formula	C₂₂H₁₅N₅O₄S₂
Molecular Weight	477.52
SMILES	O=[N+]([O-])C1=CN=C(S1)SC2=NN=C(C3=CC=CO3)N2C(C=C4)=CC=C4OCC5=CC=CC=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.