Fig. 1 · Structure
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SPDP-PEG4-NHS ester
PROTAC Linker
SPDP-PEG4-NHS ester is a PEG-based PROTAC linker designed for targeted protein degradation applications. By facilitating the conjugation of E3 ligase ligands and target proteins, this compound enhances the synthesis of PROTAC molecules, thus enabling the selective degradation of proteins of interest. Its utility in research includes the exploration of protein interactions and therapeutic development in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1334177-95-5 |
| Applications | PROTAC Linker |
| Formula | C23H33N3O9S2 |
| Molecular Weight | 559.65 |
| SMILES | O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCNC(CCSSC2=NC=CC=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.