SPDP
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs). | ||
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Catalog Num | A20578 |
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Formula | C12H12N2O4S2 |
Molecular Weight | 312.36 |
CAS Number | 68181-17-9 |
SMILES | O=C(ON1C(CCC1=O)=O)CCSSC2=NC=CC=C2 |
Synonyms | SPDP Crosslinker |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2