Fig. 1 · Structure
Documents & Downloads
Spermine Prodrug-1
Spermine Prodrug
Spermine Prodrug-1 is a redox-sensitive precursor of spermine that serves as a valuable tool for investigating Snyder-Robinson syndrome. This compound demonstrates inhibitory effects on both wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, CMS-6233) fibroblast cell lines, with IC50 values of 326.7 µM, 198.5 µM, and 244.1 µM, respectively. Its ability to modulate spermine levels makes it applicable in studies focused on cellular redox balance and related pathologies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2576358-68-2 |
| Applications | Spermine Prodrug |
| Formula | C24H45Cl3N4O5 |
| Molecular Weight | 576.00 |
| SMILES | COC1=C(C(C(C(C)(CC(NCCCNCCCCNCCCN)=O)C)=C(C1=O)C)=O)OC.[H]Cl.[H]Cl.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.