Fig. 1 · Structure
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Sphingosylphosphorylcholine
Bioactive Lipid
Sphingosylphosphorylcholine is a bioactive lipid that binds to the OGR1 receptor with a dissociation constant (Kd) of 33.3 nM. This compound promotes delayed phosphorylation of Smad2, enhances α-SMA expression, and activates the TRPM3 channel, demonstrating anti-apoptotic properties and benefits in cardiac hypertrophy and wound healing. With its ability to downregulate apoptosis while upregulating uPA and its receptor uPA-R, Sphingosylphosphorylcholine is valuable in research related to conditions such as atopic dermatitis, promyelocytic leukemia, heart failure, and various cancers, as well as skin wound healing disorders associated with diabetes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1670-26-4 |
| Applications | Bioactive Lipid |
| Formula | C23H49N2O5P |
| Molecular Weight | 464.62 |
| SMILES | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(OCC[N+](C)(C)C)([O-])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.