Fig. 1 · Structure

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Spirapril

ACE Inhibitor

Spirapril is a potent angiotensin-converting enzyme (ACE) inhibitor that effectively crosses the blood-brain barrier, exhibiting significant antihypertensive properties. By competitively binding to ACE, it inhibits the conversion of angiotensin I to angiotensin II, leading to decreased blood pressure. As an orally active prodrug of Spiraprilat, Spirapril is utilized in research related to hypertension and congestive heart failure.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 83647-97-6
Applications ACE Inhibitor
Formula C22H30N2O5S2
Molecular Weight 466.61
Synonyms SCH 33844
SMILES
CCOC([C@H](CCC1=CC=CC=C1)N[C@@H](C)C(N2CC3(SCCS3)C[C@H]2C(O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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