Fig. 1 · Structure
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Spiroglumide
CCKB Receptor Antagonist
Spiroglumide is a selective cholecystokinin B (CCKB) receptor antagonist. It demonstrates significant biological activity through the inhibition of CCKB receptor signaling, making it valuable for studying the physiological roles of cholecystokinin in various biological systems. Research applications include the investigation of gastrointestinal disorders and the exploration of potential therapeutic strategies in conditions linked with dysregulated CCKB receptor activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 137795-35-8 |
| Applications | CCKB Receptor Antagonist |
| Formula | C21H26Cl2N2O4 |
| Molecular Weight | 441.35 |
| Synonyms | CR-2194 |
| SMILES | O=C(C1=CC(Cl)=CC(Cl)=C1)N[C@H](CCC(O)=O)C(N2CCC3(CCCC3)CC2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.