Fig. 1 · Structure
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SPOP-IN-6b hydrochloride
SPOP Inhibitor
SPOP-IN-6b hydrochloride is a potent inhibitor of the speckle-type POZ protein (SPOP), exhibiting an IC50 of 3.58 μM. It serves as a crucial tool for studying the role of SPOP in various biological processes, including protein degradation and cancer progression. This compound is valuable for research applications focused on SPOP-mediated pathways and the development of targeted therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2136270-68-1 |
| Applications | SPOP Inhibitor |
| Formula | C28H33ClN6O3 |
| Molecular Weight | 537.05 |
| SMILES | O=C(C(C(N1CCC2=CC=CC=C2)=N)=CC3=C1N=C(C(C)=CC=C4)N4C3=O)NCCCN5CCOCC5.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.