Fig. 1 · Structure
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SPOP-IN-6b
SPOP Inhibitor
SPOP-IN-6b is an inhibitor of the speckle-type POZ protein (SPOP) with an IC50 value of 3.58 μM. This compound modulates SPOP activity, highlighting its potential in the study of ubiquitin-mediated degradation processes. Research applications include investigating SPOP's role in various biological pathways and its implications in diseases associated with protein misfolding and degradation dysfunction.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2136270-20-5 |
| Applications | SPOP Inhibitor |
| Formula | C28H32N6O3 |
| Molecular Weight | 500.59 |
| SMILES | O=C(C(C(N1CCC2=CC=CC=C2)=N)=CC3=C1N=C(C(C)=CC=C4)N4C3=O)NCCCN5CCOCC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.