Ke Qian, .et al. , EBioMedicine, 2023, Dec:98:104863 PMID: 37950995
Biological Activity
Description
SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 uM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets.
Targets
Target
Value
Product Information
Catalog Num
A16116
Formula
C9H11N5O
Molecular Weight
205.22
CAS Number
17318-31-9
SMILES
NC(N=CN=C12)=C2N=CN1[C@@H]3OCCC3
Synonyms
SQ 22536, SQ-22536
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro
DMSO
40 mg/mL (194.91 mM)
Water
40 mg/mL (194.91 mM)
Ethanol
40 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: