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SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 uM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets.
Targets
| Adenylyl cyclase | ||||
| In vitro | DMSO | 40 mg/mL (194.91 mM) | |
| Water | 40 mg/mL (194.91 mM) | ||
| Ethanol | 40 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 48.73 mL | 243.64 mL | 487.28 mL |
| 0.5 mM | 9.75 mL | 48.73 mL | 97.46 mL |
| 1 mM | 4.87 mL | 24.36 mL | 48.73 mL |
| 5 mM | 0.97 mL | 4.87 mL | 9.75 mL |
*The above data is based on the productmolecular weight 205.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16116 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 17318-31-9 |
| Formula | C9H11N5O |
| M. Wt | 205.22 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | SQ 22536, SQ-22536 |
| SMILES | NC(N=CN=C12)=C2N=CN1[[email protected]@H]3OCCC3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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