Fig. 1 · Structure
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Squarunkin A hydrochloride
UNC119-cargo Interaction Inhibitor
Squarunkin A hydrochloride is a selective inhibitor of the UNC119-cargo interaction, demonstrating an IC50 of 10 nM against the UNC119A-myristoylated Src N-terminal peptide. This compound effectively disrupts the activation of Src kinase in cellular environments. Squarunkin A hydrochloride serves as a valuable tool for investigating UNC119’s role in cellular signaling and its implications in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2253744-55-5 |
| Applications | UNC119-cargo Interaction Inhibitor |
| Formula | C25H33ClF3N5O4 |
| Molecular Weight | 560.01 |
| SMILES | O=C(N1CCC(NC2=C(NCCN3CCN(C4=CC=CC(C(F)(F)F)=C4)CC3)C(C2=O)=O)CC1)OCC.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.