Fig. 1 · Structure
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Squarunkin A
UNC119 Inhibitor
Squarunkin A is a selective inhibitor of UNC119, effectively disrupting the interaction between UNC119A and myristoylated Src N-terminal peptides with an IC50 of 10 nM. This inhibition leads to a blockade of Src kinase activation in cellular environments. Squarunkin A is valuable for research applications focused on SRC pathway modulation and related signal transduction studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2101958-02-3 |
| Applications | UNC119 Inhibitor |
| Formula | C25H32F3N5O4 |
| Molecular Weight | 523.55 |
| SMILES | O=C(N1CCC(NC2=C(NCCN3CCN(C4=CC=CC(C(F)(F)F)=C4)CC3)C(C2=O)=O)CC1)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.