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Biological Activity
SR 3576 is a highly potent and selective JNK3 inhibitor (IC50 = 7 nM); exhibits > 2800-fold selectivity over p38.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.94 mL | 99.69 mL | 199.39 mL |
| 0.5 mM | 3.99 mL | 19.94 mL | 39.88 mL |
| 1 mM | 1.99 mL | 9.97 mL | 19.94 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.99 mL |
*The above data is based on the productmolecular weight 501.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16020 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1164153-22-3 |
| Formula | C27H27N5O5 |
| M. Wt | 501.53 |
| Purity | >98% |
| Synonyms | JNK3 Inhibitor XII, SR-3576, SR3576 |
| SMILES | O=C(C1=CC(N2N=CC(NC(NC3=CC=CC(C)=C3)=O)=C2)=CC=C1)NC(C=C4OC)=CC(OC)=C4OC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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