SR 3576

Catalog No.: A16020

JNK3 inhibitor

SR 3576

SR 3576 Chemical Structure

CAS NO. 1164153-22-3

SR 3576 is a highly potent and selective JNK3 inhibitor (IC50 = 7 nM); exhibits > 2800-fold selectivity over p38.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
50 mg
$820.00
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Biological Activity

SR 3576 is a highly potent and selective JNK3 inhibitor (IC50 = 7 nM); exhibits > 2800-fold selectivity over p38.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.69 mL 199.39 mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16020
Actions Inhibitor
CAS No. 1164153-22-3
Formula C27H27N5O5
M. Wt 501.53
Solubility DMSO
Purity >98%
Synonyms JNK3 Inhibitor XII, SR-3576, SR3576
SMILES O=C(C1=CC(N2N=CC(NC(NC3=CC=CC(C)=C3)=O)=C2)=CC=C1)NC(C=C4OC)=CC(OC)=C4OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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