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SR 3576

JNK3 inhibitor

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Catalog No. A16020

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SR 3576 5mg A16020-5
$120.00
SR 3576 10mg A16020-10
$200.00
SR 3576 50mg A16020-50
$820.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SR 3576 is a highly potent and selective JNK3 inhibitor (IC50 = 7 nM); exhibits > 2800-fold selectivity over p38.

SR 3576

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Chemical Information

Catalog Num A16020
Actions Inhibitor
M. Wt 501.53
Formula C27H27N5O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1164153-22-3
Synonyms JNK3 Inhibitor XII, SR-3576, SR3576
SMILES O=C(C1=CC(N2N=CC(NC(NC3=CC=CC(C)=C3)=O)=C2)=CC=C1)NC(C=C4OC)=CC(OC)=C4OC

Biological Activity

Description
SR 3576 is a highly potent and selective JNK3 inhibitor (IC50 = 7 nM); exhibits > 2800-fold selectivity over p38.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.69 mL 199.39mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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