Fig. 1 · Structure
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SR-4554
Tumor Hypoxia Detection Probe
SR-4554 is a tumor hypoxia detection probe that targets hypoxic cells via enzymatic single-electron reduction reactions. It measures the 19F retention index in various mouse tumor models, including EMT6, SCCVII, KILT, and RIF-I, utilizing the 19F magnetic resonance spectroscopy (19F MRS) technique. This compound enables noninvasive detection of tumor hypoxia, facilitating research in cancer biology and therapeutic response evaluation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 167648-73-9 |
| Applications | Tumor Hypoxia Detection Probe |
| Formula | C8H9F3N4O4 |
| Molecular Weight | 282.18 |
| SMILES | O=C(NCC(O)C(F)(F)F)CN1C=CN=C1[N+]([O-])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.