SR59230A is a potent and selective antagonist of the β3-adrenergic receptor, demonstrating IC50 values of 40 nM, 408 nM, and 648 nM for β3, β1, and β2 receptors, respectively. Its ability to penetrate the blood-brain barrier makes it a valuable tool for exploring the physiological roles of β3-AR in the central nervous system. This compound is primarily utilized in research related to metabolic disorders, obesity, and cardiovascular diseases, providing insight into the therapeutic potential of β3-AR modulation.
SR59230A is a potent and selective antagonist of the β3-adrenergic receptor, demonstrating IC50 values of 40 nM, 408 nM, and 648 nM for β3, β1, and β2 receptors, respectively. Its ability to penetrate the blood-brain barrier makes it a valuable tool for exploring the physiological roles of β3-AR in the central nervous system. This compound is primarily utilized in research related to metabolic disorders, obesity, and cardiovascular diseases, providing insight into the therapeutic potential of β3-AR modulation.
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