Fig. 1 · Structure
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SR8185
Cat. No.
A79474
CAS
1356225-62-1
TBK1/IKKi Dual Inhibitor
SR8185 is a potent dual inhibitor of TBK1 and IKKi, exhibiting IC50 values of 3 nM and less than 10 nM, respectively. This compound demonstrates significant antiproliferative effects across a wide range of human cancer cell lines. SR8185 is ideal for exploring cancer-related pathways and therapeutic strategies in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1356225-62-1 |
| Applications | TBK1/IKKi Dual Inhibitor |
| Formula | C26H27N7O |
| Molecular Weight | 453.54 |
| SMILES | O=C(N1CCCC1)NC2=CC=CC(NC3=NC=CC(C4=CC=C(N5CCCC5)C(C#N)=C4)=N3)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.