Fig. 1 · Structure
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SSR 146977 hydrochloride
NK3 Receptor Antagonist
SSR 146977 hydrochloride is a selective antagonist of the tachykinin NK3 receptor. This compound exhibits significant inhibitory activity, making it a valuable tool for studying the pathophysiology of psychiatric disorders and airway inflammation. Research involving SSR 146977 hydrochloride can enhance the understanding of NK3 receptor signaling pathways and their implications in various therapeutic areas.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 264618-38-4 |
| Applications | NK3 Receptor Antagonist |
| Formula | C35H43Cl3N4O2 |
| Molecular Weight | 658.10 |
| SMILES | O=C(N(C)C)NC1(CCN(CC1)CCC[C@]2(CN(CCC2)C(C3=CC=CC=C3)=O)C4=CC=C(C(Cl)=C4)Cl)C5=CC=CC=C5.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.