Fig. 1 · Structure
Documents & Downloads
ST-539
USP30 Inhibitor
ST-539 is a potent inhibitor of the deubiquitinase USP30, exhibiting an IC50 value of 0.37 μM. By promoting the ubiquitination of mitochondrial proteins, ST-539 induces mitochondrial autophagy, contributing to the regulation of mitochondrial homeostasis. This compound is valuable for research focused on neurodegenerative diseases and the underlying mechanisms of mitochondrial dysfunction.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1040754-67-3 |
| Applications | USP30 Inhibitor |
| Formula | C30H31N3O4S |
| Molecular Weight | 529.65 |
| SMILES | O=C(NC1=C2C=CC=C(S(=O)(NC(C)(C)C)=O)C2=CC=C1)C(NC(C3=CC=CC=C3)=O)CC4=CC=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.