Stauprimide is a staurosporine analog that promotes embryonic stem cell (ESC) differentiation. It selectively binds to the MYC transcriptional regulator NME2, blocking its nuclear localization in ESCs and thereby downregulating MYC transcription.
Stauprimide is a staurosporine analog that promotes embryonic stem cell (ESC) differentiation. It selectively binds to the MYC transcriptional regulator NME2, blocking its nuclear localization in ESCs and thereby downregulating MYC transcription.
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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