Fig. 1 · Structure

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STING agonist-20-Ala-amide-PEG2-C2-NH2

Active Scaffold

STING agonist-20-Ala-amide-PEG2-C2-NH2 serves as an active scaffold targeting the stimulator of interferon genes (STING) pathway. This compound exhibits significant immune activation and can be utilized in the synthesis of immune-stimulating antibody conjugates (ISAC) for enhanced immunotherapeutic applications. Its primary use lies in cancer research, facilitating investigations into the modulation of immune responses against tumor cells.

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Specifications

Manufacturer Adooq Bioscience
Actions Activator
CAS Number 2720500-49-0
Applications Active Scaffold
Formula C46H57N13O12
Molecular Weight 984.02
SMILES
O=C(OCCCOC1=C2C(N=C(N2C/C=C/CN3C(NC(C4=C(CC)N=C(C)O4)=O)=NC5=CC(C(N)=O)=CN=C53)NC(C6=C(CC)N=C(C)O6)=O)=CC(C(N)=O)=C1)[C@@H](NC(CCOCCOCCN)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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