Fig. 1 · Structure
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STING18
STING18 is a small molecule inhibitor targeting the STING (Stimulator of Interferon Genes) protein. It exhibits effective inhibition of STING-mediated cytokine release and demonstrates favorable oral bioavailability with slow binding kinetics. This compound is valuable for research applications focused on immune modulation and the study of STING-related signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2706536-26-5 |
| Formula | C29H27ClFNO5 |
| Molecular Weight | 523.98 |
| Synonyms | Stimulator of interferon genes 18 |
| SMILES | O=C(CC1C2=CC=C(C=C2C(N(C1C3=CC=C4OCCOC4=C3)C5=CC=C(C(C)(C)C)C(Cl)=C5)=O)F)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.