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Substance P (3-11)

Catalog No.: A62106
Substance P Fragment
Substance P (3-11) is a truncated form of the neuropeptide Substance P that effectively crosses the blood-brain barrier. This fragment exhibits potent contracting activity on guinea pig ileum and stimulates chemotaxis in human monocytes. It is utilized in research focused on neuroinflammation, pain pathways, and immune response modulation.
Substance P (3-11) 51165-11-8 Substance P Fragment
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSubstance P (3-11) is a truncated form of the neuropeptide Substance P that effectively crosses the blood-brain barrier. This fragment exhibits potent contracting activity on guinea pig ileum and stimulates chemotaxis in human monocytes. It is utilized in research focused on neuroinflammation, pain pathways, and immune response modulation.
Product Information
Catalog NumA62106
FormulaC52H79N13O11S
Molecular Weight1094.33
CAS Number51165-11-8
SequenceLys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
Sequence shorteningKPQQFFGLM-NH2
SMILESC(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(NCC(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)=O)=O)=O)CCC(N)=O)=O)CCC(N)=O)(=O)[C@H]3N(C([C@H](CCCCN)N)=O)CCC3
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GPCR/G Protein > Neurokinin Receptors