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Substance P-Gly-Lys-Arg

Catalog No.: A62098
Analog of Substance P
Substance P-Gly-Lys-Arg is an analog of Substance P designed to interact with neurokinin receptors. This peptide exhibits key biological activity in modulating pain perception and inflammatory responses, making it a valuable tool for studying neuropeptide signaling pathways. Research applications include investigating the role of Substance P in pain management and exploring therapeutic avenues for neuroinflammatory conditions.
Substance P-Gly-Lys-Arg 123148-51-6 Analog of Substance P
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSubstance P-Gly-Lys-Arg is an analog of Substance P designed to interact with neurokinin receptors. This peptide exhibits key biological activity in modulating pain perception and inflammatory responses, making it a valuable tool for studying neuropeptide signaling pathways. Research applications include investigating the role of Substance P in pain management and exploring therapeutic avenues for neuroinflammatory conditions.
Product Information
Catalog NumA62098
FormulaC77H124N24O17S
Molecular Weight1690.02
CAS Number123148-51-6
Sequence shorteningRPKPQQFFGLMGKR
SMILESCSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
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GPCR/G Protein > Neurokinin Receptors