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Succinyl CoA

Coenzyme A Derivative

Succinyl CoA, a key coenzyme A derivative, serves as a crucial intermediate in the tricarboxylic acid cycle. It is synthesized from α-ketoglutarate or propionyl-CoA and functions as an essential precursor for heme biosynthesis and gluconeogenesis. Deficiency of Succinyl CoA, particularly due to cobalamin deficiency, is associated with growth retardation, impaired heme synthesis, tissue glycine accumulation, and neurological disorders. This compound is valuable for research into metabolic, neurological, and hematological conditions, including those resulting from vitamin B12 deficiency that leads to reduced Succinyl CoA levels.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	604-98-8
Applications	Coenzyme A Derivative
Formula	C₂₅H₄₀N₇O₁₉P₃S
Molecular Weight	867.61
Synonyms	Succinyl-coenzyme A; S-(Hydrogen succinyl)coenzyme A
SMILES	O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CCC(O)=O)=O)=O)=O)(O)=O)(O)=O)O[C@H]1N2C=NC3=C(N)N=CN=C32

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.