Sudan IV-d6 is a deuterium-labeled analog of Sudan IV, acting as an agonist of the aryl hydrocarbon receptor (AhR). It activates downstream signaling pathways, leading to the induction of CYP1A1 expression, which plays a crucial role in drug metabolism. This reagent is valuable for investigating the toxicity mechanisms of industrial dyes and understanding their interactions with serum proteins, such as bovine serum albumin (BSA). Additionally, Sudan IV-d6 functions as a fat-soluble diazo dye, suitable for lipid, triglyceride, and lipoprotein staining in frozen tissue sections.
Sudan IV-d6 is a deuterium-labeled analog of Sudan IV, acting as an agonist of the aryl hydrocarbon receptor (AhR). It activates downstream signaling pathways, leading to the induction of CYP1A1 expression, which plays a crucial role in drug metabolism. This reagent is valuable for investigating the toxicity mechanisms of industrial dyes and understanding their interactions with serum proteins, such as bovine serum albumin (BSA). Additionally, Sudan IV-d6 functions as a fat-soluble diazo dye, suitable for lipid, triglyceride, and lipoprotein staining in frozen tissue sections.
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