Fig. 1 · Structure
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Sulfadoxine
Antiparasitic Agent
Sulfadoxine is a long-acting sulfonamide antiparasitic agent that primarily inhibits the growth of parasites by blocking dihydropteroate synthase in the folate synthesis pathway. It is commonly used in combination therapies for the treatment of malaria and can also be effective against certain bacterial infections, including those of the respiratory and urinary tracts. Additionally, sulfadoxine has been shown to inhibit HIV replication in peripheral blood mononuclear cells, making it of interest in virology research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2447-57-6 |
| Applications | Antiparasitic Agent |
| Formula | C12H14N4O4S |
| Molecular Weight | 310.33 |
| Synonyms | Sulphadoxine |
| SMILES | O=S(NC1=NC=NC(OC)=C1OC)(C2=CC=C(N)C=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.