Sulfamethizole-d4-1 is a deuterium-labeled derivative of Sulfamethizole, a sulfathiazole antibiotic. This compound inhibits the synthesis of folic acid and thymine, selectively reducing bioluminescence in Photobacterium phosphoreum. Sulfamethizole demonstrates antibacterial activity against Escherichia coli related to urinary tract infections, while exhibiting no effects on sulII gene-positive strains. It is primarily utilized in research focused on urinary tract infections and the mechanisms underlying Photobacterium phosphoreum bioluminescence.
Sulfamethizole-d4-1 is a deuterium-labeled derivative of Sulfamethizole, a sulfathiazole antibiotic. This compound inhibits the synthesis of folic acid and thymine, selectively reducing bioluminescence in Photobacterium phosphoreum. Sulfamethizole demonstrates antibacterial activity against Escherichia coli related to urinary tract infections, while exhibiting no effects on sulII gene-positive strains. It is primarily utilized in research focused on urinary tract infections and the mechanisms underlying Photobacterium phosphoreum bioluminescence.
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