Sulfo-DMAC-SPP

Catalog No.: A43047
ADC Linker
Sulfo-DMAC-SPP is a cleavable linker specifically designed for the construction of antibody-drug conjugates (ADCs). This reagent facilitates the selective attachment of cytotoxic agents to antibodies, thereby enhancing targeted delivery and efficacy in cancer therapy. Its incorporation into ADCs can improve therapeutic profiles by allowing controlled release of the drug within the tumor microenvironment, making it valuable for advancing research in targeted cancer treatments.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSulfo-DMAC-SPP is a cleavable linker specifically designed for the construction of antibody-drug conjugates (ADCs). This reagent facilitates the selective attachment of cytotoxic agents to antibodies, thereby enhancing targeted delivery and efficacy in cancer therapy. Its incorporation into ADCs can improve therapeutic profiles by allowing controlled release of the drug within the tumor microenvironment, making it valuable for advancing research in targeted cancer treatments.
Product Information
Catalog NumA43047
FormulaC17H21N3O8S3
Molecular Weight491.56
CAS Number663599-11-9
SMILESCC(SSC1=C(C(N(C)C)=O)C=NC=C1)CCC(ON2C(C(S(=O)(O)=O)CC2=O)=O)=O
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