Fig. 1 · Structure
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Sulfo galactosylceramide
Glycolipid
Sulfo galactosylceramide is a glycolipid that serves as a critical component of mature myelin. It has been shown to interact with C-type lectins and immunoglobulin-like receptors, particularly exhibiting high affinity for LMIR5. This compound induces MCP-1 production in basophils and enhances NFAT activation through LMIR5. In research applications, sulfo galactosylceramide demonstrates therapeutic potential by alleviating symptoms and improving survival in mouse models of chronic relapsing-remitting experimental autoimmune encephalomyelitis (EAE), while also reducing inflammatory lesions and infiltrating mononuclear cells in spinal cord tissues.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 151057-28-2 |
| Applications | Glycolipid |
| Formula | C48H91NO11S |
| Molecular Weight | 890.30 |
| Synonyms | (3'-sulfo)Galβ-Cer(d18:1/24:1); N-Nervonoyl Sulfatide; C24:1 Sulfatide |
| SMILES | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H]1[C@@H]([C@H]([C@@H](O)[C@@H](CO)O1)OS(=O)(O)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.