Fig. 1 · Structure
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Sulfo-NHS-Acetate
PROTAC Linker
Sulfo-NHS-Acetate is a PROTAC linker that enables the synthesis of proteolysis-targeting chimeras (PROTACs) through the formation of stable amide bonds. This compound features an alkyl chain that facilitates the conjugation of various target proteins, enhancing the efficacy of targeted protein degradation. It serves as an essential building block for researchers aiming to develop innovative therapeutics in targeted protein modulation and degradation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 152305-87-8 |
| Applications | PROTAC Linker |
| Formula | C6H7NO7S |
| Molecular Weight | 237.19 |
| SMILES | O=S(C(C1)C(N(OC(C)=O)C1=O)=O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.