Sutherlandin trans-p-coumarate is a selective γ-hydroxynitrile glycoside that acts as an anti-inflammatory agent by inhibiting nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages, demonstrating 56.9% inhibition at a concentration of 25 μg/mL. This compound can be naturally extracted from the dried aerial parts of Sorbaria sorbifolia, a member of the Rosaceae family. Due to its biological activity, it is of interest in research focused on inflammation and immune response modulation.
Sutherlandin trans-p-coumarate is a selective γ-hydroxynitrile glycoside that acts as an anti-inflammatory agent by inhibiting nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages, demonstrating 56.9% inhibition at a concentration of 25 μg/mL. This compound can be naturally extracted from the dried aerial parts of Sorbaria sorbifolia, a member of the Rosaceae family. Due to its biological activity, it is of interest in research focused on inflammation and immune response modulation.
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