Fig. 1 · Structure
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Suvigletistat
Glutaminase Inhibitor
Suvigletistat is a potent glutaminase inhibitor, demonstrating an IC50 value of less than 0.5 µM. This compound is designed to disrupt the activity of transglutaminase 2 (TG2), which plays a crucial role in various metabolic processes. Research applications include studying metabolic dysregulation and the potential therapeutic effects in cancer and neurodegenerative diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2410912-75-1 |
| Applications | Glutaminase Inhibitor |
| Formula | C28H36N6O5 |
| Molecular Weight | 536.62 |
| SMILES | CN(C)C(/C=C/CC[C@H](NC(OC)=O)C(NC1=CC=CN(CC2=NC3=CC=CC(CC(C)C)=C3N2)C1=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.