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Form	MW
SV119 hydrochloride This page	476.48
SV119	403.56

SV119 hydrochloride

Sigma-2 Ligand

SV119 hydrochloride is a sigma-2 ligand with a Ki value of 5.2 nM that enhances the translocation of therapeutic agents across the plasma membrane of cancer cells. It has shown the ability to overcome the internalization barrier in pancreatic cancer, effectively maintaining the anti-tumor properties of conjugated dm-Erastin. Furthermore, SV119 hydrochloride exhibits cytotoxic effects on triple-negative breast cancer (TNBC) cells and promotes apoptosis, making it a valuable compound for cancer research and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	913816-12-3
Applications	Sigma-2 Ligand
Formula	C₂₃H₃₉Cl₂N₃O₃
Molecular Weight	476.48
SMILES	NCCCCCCN([C@@]1([H])C2)[C@](CCC1)([H])C[C@H]2OC(NC(C=C3C)=C(C=C3)OC)=O.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.