Fig. 1 · Structure
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(+)-Syringaresinol (d-Syringaresinol)
NFAT Transcription Factor Inhibitor
(+)-Syringaresinol is a lignan that acts as an inhibitor of the NFAT transcription factor, exhibiting an IC50 of 329.4 μM. This compound is significant in the study of lymphocytic leukemia and other conditions related to NFAT pathway dysregulation. Its role in modulating transcriptional activity makes it a valuable tool for researchers investigating NFAT's involvement in various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 21453-69-0 |
| Applications | NFAT Transcription Factor Inhibitor |
| Formula | C22H26O8 |
| Molecular Weight | 418.44 |
| Synonyms | d-Syringaresinol |
| SMILES | OC1=C(C=C(C=C1OC)[C@@H]2[C@@]3([C@]([H])(CO2)[C@H](OC3)C4=CC(OC)=C(C(OC)=C4)O)[H])OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.