SZM-1209 is a potent and specific inhibitor of RIPK1, demonstrating a Kd of 85 nM. It exhibits significant anti-necroptotic activity with an EC50 value of 22.4 ± 8.1 nM. SZM-1209 has been shown to mitigate conditions associated with systemic inflammatory response syndrome (SIRS) and acute lung injury (ALI), making it a valuable tool for research in inflammation-related pathologies.
SZM-1209 is a potent and specific inhibitor of RIPK1, demonstrating a Kd of 85 nM. It exhibits significant anti-necroptotic activity with an EC50 value of 22.4 ± 8.1 nM. SZM-1209 has been shown to mitigate conditions associated with systemic inflammatory response syndrome (SIRS) and acute lung injury (ALI), making it a valuable tool for research in inflammation-related pathologies.
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