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T 162559

NHE1 Inhibitor

T 162559 is a highly potent and selective inhibitor of the Na+/H+ exchanger isoform NHE1, displaying an IC50 of 0.96 nM. This compound is uniquely selective, showing no inhibition of Na+/HCO3- cotransport or Na+/Ca2+ exchange. T 162559 is valuable for research into cardiovascular diseases, providing insights into the role of NHE1 in cellular ionic balance and cardiac function.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	339532-12-6
Applications	NHE1 Inhibitor
Formula	C₂₀H₂₈FN₅O₆S₂
Molecular Weight	517.59
SMILES	CS(=O)(O)=O.CS(=O)(O)=O.CC1=C([C@@H]2C/C(C3=C(C)C=CN=C3C2)=N\NC(N)=N)C=C(F)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.