Fig. 1 · Structure
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T 26c sodium
MMP-13 Inhibitor
T26c sodium is a highly potent and selective inhibitor of MMP-13, exhibiting an IC50 value of 6.9 pM. This compound effectively prevents the degradation of bovine nasal septal cartilage explants, making it a valuable tool for research into cartilage metabolism and tissue preservation. T26c sodium is particularly useful in studies related to arthritis and other degenerative joint diseases where MMP-13 plays a critical role in extracellular matrix remodeling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 869298-22-6 |
| Applications | MMP-13 Inhibitor |
| Formula | C24H19N3Na2O6S |
| Molecular Weight | 523.47 |
| SMILES | O=C(NCC1=CC(OC)=CC=C1)C(N(C2=C3C(COCC4=CC=C(C(O[Na])=O)C=C4)=CS2)[Na])=NC3=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.