Fig. 1 · Structure

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T-3764518

Cat. No. A20150 CAS 1809151-56-1

SCD inhibitor

T-3764518 is a novel and potent stearoyl coenzyme A desaturase (SCD) inhibitor with an IC50 of 4.7 nM.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
HCT-116 GI50 2.7 nM Growth inhibition of human HCT116 cells after 72 hrs by CellTiter-Glo luminescence assay [PMID: 28571972]

Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1809151-56-1
Applications SCD inhibitor
Formula C20H17F6N5O2
Molecular Weight 473.37
SMILES
OCC1=NN=C(C2=CC=C(N3CCC(C4=CC=C(C(F)(F)F)C=C4)(C(F)(F)F)CC3)N=N2)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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