Fig. 1 · Structure

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TA-270

Cat. No. A76450 CAS 194037-25-7

5-Lipoxygenase Inhibitor

TA-270 is a potent inhibitor of 5-lipoxygenase, an enzyme involved in the biosynthesis of leukotrienes, which are key mediators in inflammatory processes. This quinolinone derivative is primarily utilized in asthma research to elucidate the role of leukotrienes in airway inflammation and hyperreactivity. Its selective inhibition of 5-lipoxygenase provides a valuable tool for investigating therapeutic strategies aimed at respiratory conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 194037-25-7
Applications 5-Lipoxygenase Inhibitor
Formula C29H36N2O7
Molecular Weight 524.61
SMILES
O=C(NC1=CC2=C(C=C1)C(O)=C(OCCCCCCCC)C(N2C)=O)/C=C/C3=CC(OC)=C(O)C(OC)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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