TAK-243
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination. |
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Catalog Num | A20369 |
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Formula | C19H20F3N5O5S2 |
Molecular Weight | 519.52 |
CAS Number | 1450833-55-2 |
SMILES | O=S(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](NC2=CC=NC3=CC(C4=CC=CC(SC(F)(F)F)=C4)=NN23)C1)(N)=O |
Synonyms | TAK 243, TAK243, MLN7243, MLN 7243, MLN-7243 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 85 mg/mL (163.61 mM) | |
Water | Insoluble | ||
Ethanol | 21 mg/mL (40.42 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.25 mL | 96.24 mL | 192.49 mL |
0.5 mM | 3.85 mL | 19.25 mL | 38.5 mL |
1 mM | 1.92 mL | 9.62 mL | 19.25 mL |
5 mM | 0.38 mL | 1.92 mL | 3.85 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2