TAK-659

Catalog No.: A20450
SYK/FLT3 inhibitor
TAK-659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively.
Grouped product items
Product Name Price Stock Qty
TAK-659 5mg
$126.00
In stock
TAK-659 10mg
$217.00
In stock
TAK-659 50mg
$644.00
In stock
TAK-659 100mg
$1,288.00
In stock
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Biological Activity
Discription TAK-659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively.
Product Information
Catalog Num A20450
Formula C17H21FN6O
Molecular Weight 344.39
CAS Number 1312691-33-0
SMILES FC1=C(N[C@@H]2CCCC[C@@H]2N)N=C(C3=CN(C)N=C3)C4=C1CNC4=O
Synonyms TAK659, TAK 659
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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