Biological Activity
Takinib is a selective TAK1 inhibitor that induces apoptosis following TNF-α stimulation in cell models of rheumatoid arthritis and metastatic breast cancer.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 31.02 mL | 155.11 mL | 310.21 mL |
0.5 mM | 6.2 mL | 31.02 mL | 62.04 mL |
1 mM | 3.1 mL | 15.51 mL | 31.02 mL |
5 mM | 0.62 mL | 3.1 mL | 6.2 mL |
*The above data is based on the productmolecular weight 322.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16960 |
---|---|
Actions | Inhibitor |
M. Wt | 322.36 |
Formula | C18H18N4O2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1111556-37-6 |
Synonyms | EDHS-206, EDHS 206, EDHS206 |
SMILES | O=C(C1=CC=CC(C(NC2=NC3=CC=CC=C3N2CCC)=O)=C1)N |
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