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Taltobulin intermediate-11

Intermediate

Taltobulin intermediate-11 is a critical intermediate in the synthesis of Taltobulin, a potent tubulin inhibitor that plays a significant role in the preparation of antibody-drug conjugates (ADCs). This compound disrupts tubulin polymerization, leading to mitotic arrest and subsequent apoptosis in cancer cells. Taltobulin is utilized in various research applications targeting microtubule dynamics and cancer therapeutics development.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1822561-77-2
Applications	Intermediate
Formula	C₁₇H₂₅NO₄
Molecular Weight	307.38
SMILES	O=C(NC(C(C)(C)C1=CC=CC=C1)C(OC)=O)OC(C)(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.