Fig. 1 · Structure

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Taltobulin intermediate-5

Intermediate

Taltobulin intermediate-5 is a key precursor in the synthesis of Taltobulin, a potent tubulin inhibitor. Taltobulin demonstrates significant biological activity by disrupting tubulin polymerization, leading to mitotic arrest and subsequent apoptosis. This compound is essential for research applications involving antibody-drug conjugate (ADC) preparations, where effective cytotoxic agents are required for targeted cancer therapies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2459946-53-1
Applications Intermediate
Formula C11H22ClNO2
Molecular Weight 235.75
SMILES
CC([C@H](/C=C(C)/C(OCC)=O)NC)C.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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