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TAM557

Tubulysin

TAM557 is a cytotoxic tubulysin derivative that primarily targets microtubule dynamics, inhibiting cell proliferation. This compound is useful in enzymatic conjugation reactions and is applicable in cancer research, particularly in studying mechanisms of drug resistance and cellular responses to microtubule-targeting agents. Its ability to disrupt microtubule organization makes it a valuable tool in the investigation of cytotoxicity and tumor biology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1802499-20-2
Applications	Tubulysin
Formula	C₅₀H₈₄N₈O₁₁S
Molecular Weight	1005.31
SMILES	O=C([C@@H]1N(CCCC1)C)N[C@@H]([C@@H](C)CC)C(N(CCC)[C@@H](C(C)C)C[C@H](C2=NC(C(N[C@H](C[C@H](C)C(NNC(OCCOCCOCCOCCN)=O)=O)CC3=CC=C(C=C3)O)=O)=CS2)OCCC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.